sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptide
SIGMAR1
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN5513637
Quick Overview for sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptide (ABIN5513637)
Target
SIGMAR1
(sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
-
-
Protein Region
- Middle Region
-
Sequence
- PGEATAVEWG PNTWMVEYGR GVIPSTLAFA LADTVFSTQD FLTLFYTLRS
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- SIGMAR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
-
Background
-
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1
Protein Size: 223 -
Gene ID
- 10280
-
NCBI Accession
- NM_001282205, NP_001269134
-
UniProt
- Q99720
Target
-
You are here:
