SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (N-Term) Peptide
SRGAP2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513729
Quick Overview for SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (N-Term) Peptide (ABIN5513729)
Target
SRGAP2
(SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- AERFLAKTCS TKDQQFKKDQ NVLSPVNCWN LLLNQVKRES RDHTTLSDIY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- SRGAP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
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Background
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This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.
Alias Symbols: FNBP2, SRGAP3, SRGAP2A, ARHGAP34
Protein Size: 459 -
Gene ID
- 23380
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NCBI Accession
- NM_001170637, NP_001258799
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UniProt
- P0DJJ0
Target
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