Peroxisomal Biogenesis Factor 12 (PEX12) (Middle Region) Peptide
PEX12
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5518157
$160.46
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100 μg
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Quick Overview for Peroxisomal Biogenesis Factor 12 (PEX12) (Middle Region) Peptide (ABIN5518157)
Target
PEX12
(Peroxisomal Biogenesis Factor 12 (PEX12))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SIMFLVLLPY LKVKLEKLVS SLREEDEYSI HPPSSRWKRF YRAFLAAYPF
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEX12 (Peroxisomal Biogenesis Factor 12 (PEX12))
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Background
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This gene belongs to the peroxin-12 family. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS).
Alias Symbols: PAF-3, PBD3A
Protein Size: 167 -
Gene ID
- 5193
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NCBI Accession
- NM_000286, NP_000277
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UniProt
- O00623
Target
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