6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) Peptide
PFKFB2
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5518158
Quick Overview for 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (C-Term) Peptide (ABIN5518158)
Target
PFKFB2
(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- YLRCPLHTIF KLTPVAYGCK VETIKLNVEA VNTHRDKPTN NFPKNQTPVR
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
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Background
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The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: PFK-2/FBPase-2
Protein Size: 167 -
Gene ID
- 5208
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NCBI Accession
- NM_001018053, NP_001018063
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UniProt
- O60825
Target
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