SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2) (Middle Region) Peptide
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- Target See all SRGAP2 products
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- MYNADSISAQ SKLKEAEKQE EKQIGKSVKQ EDRQTPRSPD STANVRIEEK
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))
- Background
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This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.
Alias Symbols: FNBP2, SRGAP3, SRGAP2A, ARHGAP34
Protein Size: 167 - Gene ID
- 23380
- NCBI Accession
- NM_001170637, NP_001164108
- UniProt
- O75044
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