Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Middle Region) Peptide
SIGLEC8
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5518360
Quick Overview for Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Middle Region) Peptide (ABIN5518360)
Target
SIGLEC8
(Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VRSCRKKSAR PAAGVGDTGM EDAKAIRGSA SQGPLTESWK DGNPLKKPPP
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Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) peptide
SIGLEC8 Reactivity: Human Host: Synthetic BP, Imm
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Background
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Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010]
Alias Symbols: SAF2, SIGLEC-8, SIGLEC8L
Protein Size: 201 -
Gene ID
- 27181
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NCBI Accession
- NM_014442, NP_055257
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UniProt
- Q9NYZ4
Target
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