Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (C-Term) Peptide
Quick Overview for Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (C-Term) Peptide (ABIN5518472)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- IEIAYKRHKD ARRKQMQLAF AAVNVWRKNL QDRKSGRAEP DPKKKATFRA
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GRIN1/NMDAR1 (GRIN1) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1))
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Background
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The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described.
Alias Symbols: NR1, MRD8, GluN1, NMDA1, NMD-R1, NMDAR1,
Protein Size: 938 -
Gene ID
- 2902
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NCBI Accession
- NM_000832, NP_000823
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UniProt
- Q05586
Target
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