sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1) (Middle Region) Peptide
SIGMAR1
Reactivity: Human
Host: Synthetic
WB
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- Target See all SIGMAR1 products
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- AVEWGPNTWM VEYGRGVIPS TLAFALADTV FSTQDFLTLF YTLRSYARGL
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SIGMAR1 (sigma Non-Opioid Intracellular Receptor 1 (SIGMAR1))
- Background
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This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor, it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Alias Symbols: SRBP, ALS16, OPRS1, SR-BP, SIG-1R, SR-BP1, sigma1R, hSigmaR1
Protein Size: 223 - Gene ID
- 10280
- NCBI Accession
- NM_001282205, NP_001269134
- UniProt
- Q99720
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