Polymerase (DNA Directed), beta (POLB) (Middle Region) Peptide
POLB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671537
Quick Overview for Polymerase (DNA Directed), beta (POLB) (Middle Region) Peptide (ABIN5671537)
Target
POLB
(Polymerase (DNA Directed), beta (POLB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- EDLRKNEDKL NHHQRIGLKY FGDFEKRIPR EEMLQMQDIV LNEVKKVDSE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- POLB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POLB (Polymerase (DNA Directed), beta (POLB))
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Background
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The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Protein Size: 335 -
Gene ID
- 5423
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NCBI Accession
- NM_002690, NP_002681
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UniProt
- P06746
Target
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