Polymerase (DNA Directed), beta (POLB) (Middle Region) Peptide
POLB
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POLB products
- POLB (Polymerase (DNA Directed), beta (POLB))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LSKGETKFMG VCQLPSKNDE KEYPHRRIDI RLIPKDQYYC GVLYFTGSDI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- POLB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POLB (Polymerase (DNA Directed), beta (POLB))
- Background
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The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Protein Size: 335 - Gene ID
- 5423
- NCBI Accession
- NM_002690, NP_002681
- UniProt
- P06746
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