Epithelial Cell Transforming Sequence 2 Oncogene (ECT2) (Middle Region) Peptide
ECT2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ECT2 products
- ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IRPVQRLPSV ALLLNDLKKH TADENPDKST LEKAIGSLKE VMTHINEDKR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ECT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))
- Background
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The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ARHGEF31
Protein Size: 958 - Gene ID
- 1894
- NCBI Accession
- NM_001258315, NP_001245244
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