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IgG3 (Middle Region) Peptide

Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5671649
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 16 Business Days

Quick Overview for IgG3 (Middle Region) Peptide (ABIN5671649)

Target

IgG3

Origin

Human

Source

  • 3
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    Middle Region

    Sequence

    TKNQVSLTCL VKGFYPSDIA VEWESSGQPE NNYNTTPPML DSDGSFFLYS

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- IGHG3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    IgG3

    Target Type

    Antibody

    Background

    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

    Alias Symbols: IgG3

    Protein Size: 377

    Gene ID

    3502

    UniProt

    P01860
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