Ring Finger Protein 216 (RNF216) (Middle Region) Peptide
RNF216
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671850
Quick Overview for Ring Finger Protein 216 (RNF216) (Middle Region) Peptide (ABIN5671850)
Target
RNF216
(Ring Finger Protein 216 (RNF216))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TEDDEKLIEE IQKEAEEEQK RKNGENTFKR IGPPLEKPVE KVQRVEALPR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- RNF216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNF216 (Ring Finger Protein 216 (RNF216))
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Background
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This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
Alias Symbols: ZIN, CAHH, U7I1, TRIAD3, UBCE7IP1
Protein Size: 923 -
Gene ID
- 54476
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NCBI Accession
- NM_207111, NP_996994
Target
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