XiAP Associated Factor 1 (XAF1) (Middle Region) Peptide
XAF1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671967
Quick Overview for XiAP Associated Factor 1 (XAF1) (Middle Region) Peptide (ABIN5671967)
Target
XAF1
(XiAP Associated Factor 1 (XAF1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- KTLDPLLMSE PKPRTSSPRG DKAAYDILRR CSQCGILLPL PILNQHQEKC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- XAF1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- XAF1 (XiAP Associated Factor 1 (XAF1))
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Background
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This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: BIRC4BP, XIAPAF1, HSXIAPAF1
Protein Size: 301 -
Gene ID
- 54739
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NCBI Accession
- NM_017523, NP_059993
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UniProt
- Q6GPH4
Target
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