Myosin Phosphatase rho Interacting Protein (MPRIP) (N-Term) Peptide
MPRIP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672104
Quick Overview for Myosin Phosphatase rho Interacting Protein (MPRIP) (N-Term) Peptide (ABIN5672104)
Target
MPRIP
(Myosin Phosphatase rho Interacting Protein (MPRIP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- RTNKQNQKKK RKVEPPTPQE PGPAKVAVTS SSSSSSSSSS IPSAEKVPTT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MPRIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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Background
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Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
Alias Symbols: MRIP, RIP3, M-RIP, RHOIP3, p116Rip
Protein Size: 1000 -
Gene ID
- 23164
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NCBI Accession
- NM_015134, NP_055949
Target
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