Superoxide Dismutase 2, Mitochondrial (SOD2) (Middle Region) Peptide
SOD2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672197
Quick Overview for Superoxide Dismutase 2, Mitochondrial (SOD2) (Middle Region) Peptide (ABIN5672197)
Target
SOD2
(Superoxide Dismutase 2, Mitochondrial (SOD2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- NGGGHINHSI FWTNLSPNGG GEPKGELLEA IKRDFGSFDK FKEKLTAASV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- SOD2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
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Background
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This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Alias Symbols: IPOB, IPO-B, MNSOD, MVCD6, Mn-SOD
Protein Size: 222 -
Gene ID
- 6648
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NCBI Accession
- NM_000636, NP_000627
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UniProt
- P04179
Target
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