Superoxide Dismutase 2, Mitochondrial (SOD2) (Middle Region) Peptide
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- Target See all SOD2 products
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NGGGHINHSI FWTNLSPNGG GEPKGELLEA IKRDFGSFDK FKEKLTAASV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SOD2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))
- Background
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This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Alias Symbols: IPOB, IPO-B, MNSOD, MVCD6, Mn-SOD
Protein Size: 222 - Gene ID
- 6648
- NCBI Accession
- NM_000636, NP_000627
- UniProt
- P04179
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