Thyroid Hormone Receptor Interactor 4 (TRIP4) (Middle Region) Peptide
Quick Overview for Thyroid Hormone Receptor Interactor 4 (TRIP4) (Middle Region) Peptide (ABIN5672293)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- QCFKKDEILD GQKSGDHLKR GRKKGRNRQE VPAFTEPDTT AEVKTPFDLA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TRIP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIP4 (Thyroid Hormone Receptor Interactor 4 (TRIP4))
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Background
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Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation. Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. May play a role in the development of neuromuscular junction. May play a role in late myogenic differentiation (By similarity).
Alias Symbols: ASC1, ASC-1, ZC2HC5, HsT17391
Protein Size: 581 -
Gene ID
- 9325
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NCBI Accession
- NM_016213, NP_057297
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UniProt
- Q15650
Target
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