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ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (C-Term) Peptide

ARFGAP1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672345
  • Target See all ARFGAP1 products
    ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    TERRSSDSWE VWGSASTNRN SNSDGGEGGE GTKKAVPPAV PTDDGWDNQN
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- ARFGAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
    Background
    The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

    Alias Symbols: ARF1GAP, HRIHFB2281

    Protein Size: 293
    Gene ID
    55738
    NCBI Accession
    NM_001281482, NP_001268411
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