Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (Middle Region) Peptide
RAPGEF4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672626
Quick Overview for Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4) (Middle Region) Peptide (ABIN5672626)
Target
RAPGEF4
(Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- LEKIVKQISE DAKAPQKKHK VLLQQFNTGD ERAQKRQPIR GSDEVLFKVY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RPGF4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))
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Background
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RPGF4 is a guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. It seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2.
Alias Symbols: RAPGEF4,CGEF2, EPAC2,
Protein Size: 696 -
Gene ID
- 11069
Target
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