X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (N-Term) Peptide
XRCC6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672698
Quick Overview for X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6) (N-Term) Peptide (ABIN5672698)
Target
XRCC6
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- SSDRDLLAVV FYGTEKDKNS VNFKNIYVLQ ELDNPGAKRI LELDQFKGQQ
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti- XRCC6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- XRCC6 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))
-
Background
-
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Alias Symbols: ML8, KU70, TLAA, CTC75, CTCBF, G22P1
Protein Size: 609 -
Gene ID
- 2547
-
NCBI Accession
- NM_001288976, NP_001275905
-
UniProt
- P12956
Target
-
You are here:
