rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2) (C-Term) Peptide
Quick Overview for rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2) (C-Term) Peptide (ABIN5673155)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- VHRNFEDRER QELGSPEERL QDSSDPDTGS EEEGSSRLSP PHSPRDFTRM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- ARHGEF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
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Background
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: GEF, P40, GEFH1, LFP40, GEF-H1
Protein Size: 986 -
Gene ID
- 9181
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NCBI Accession
- NM_001162383, NP_001155855
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UniProt
- Q92974
Target
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