phosphodiesterase 11A (PDE11A) (Middle Region) Peptide
PDE11A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5673488
Quick Overview for phosphodiesterase 11A (PDE11A) (Middle Region) Peptide (ABIN5673488)
Target
PDE11A
(phosphodiesterase 11A (PDE11A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GKGIIGYVGE HGETVNIPDA YQDRRFNDEI DKLTGYKTKS LLCMPIRSSD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PDE11A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PDE11A (phosphodiesterase 11A (PDE11A))
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Background
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The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PPNAD2
Protein Size: 933 -
Gene ID
- 50940
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NCBI Accession
- NM_001077196, NP_001070664
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UniProt
- Q9HCR9
Target
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