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Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptide

HNRPDL Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5673562

Quick Overview for Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL) (C-Term) Peptide (ABIN5673562)

Target

HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

Origin

Human

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    NYSGYGGYDY TGYNYGNYGY GQGYADYSGQ QSTYGKASRG GGNHQNNYQP

    Characteristics

    This is a synthetic peptide designed for use in combination with anti- HNRPDL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))

    Background

    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.

    Alias Symbols: HNRNP, JKTBP, HNRPDL, JKTBP2, LGMD1G, laAUF1

    Protein Size: 244

    Gene ID

    9987

    NCBI Accession

    NM_001207000, NP_001193929
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