Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptide
PES1
Reactivity: Human
Host: Synthetic
WB, BP
Catalog No. ABIN5673777
Quick Overview for Pescadillo Ribosomal Biogenesis Factor 1 (PES1) (Middle Region) Peptide (ABIN5673777)
Target
PES1
(Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB), Blocking Peptide (BP)
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Protein Region
- Middle Region
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Sequence
- LQRGEDPGNL NESEEEEEED DNNEGDGDEE GENEEEEEDA EAGSEKEEEA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PES1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))
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Background
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This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
Alias Symbols: PES
Protein Size: 588 -
Gene ID
- 23481
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NCBI Accession
- NM_001243225, NP_001230154
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UniProt
- O00541
Target
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