Galanin (GAL) Peptide
GAL
Reactivity: Human
Host: Synthetic
BP, Func
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- Target See all Galanin (GAL) products
- Galanin (GAL)
- Peptide Type
- Synthetic
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Functional Studies (Func)
- Purpose
- A Non-Selective and Potent Agonist of Galanin Receptors
- Sequence
- GWTLNSAGYL LGPHAVGNHR SFSDKNGLTS -OH
- Specificity
- Toxin target: Galanin receptors
- Characteristics
- A Non-Selective and Potent Agonist of Galanin Receptors
- Purity
- ≥98 % (HPLC)
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Galanin (GAL) peptide (Ovalbumin)
GAL Reactivity: Human Host: Synthetic Imm, SDS, WB
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- Application Notes
- Antigen Preadsorption Control: 1 - 10 nM
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing, light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 μM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
- Buffer
- Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
- Storage
- 4 °C,-20 °C
- Storage Comment
- The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.,The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.
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- Target
- Galanin (GAL)
- Background
- Galanin is a peptide hormone that acts as a non-selective and potent galanin receptor agonist. In human, Galanin is a C-terminal-amidated 30-residue peptide deriving its name from the N-terminal glycine and C-terminal alanine residue1,2. Galanin receptors belong to the family of G-protein coupled receptors and consist of three subtypes: GalR1, GalR2, and GalR3.Galanin is widely distributed through the central and peripheral nervous system and its biological activity includes contraction or relaxation of gut smooth muscles, inhibition of insulin and somatostatin release, and modulation of hormone secretion from the pituitary and adrenal glands. It is believed that galanin plays an important role as a neuromodulator of endocrine secretion and synaptic transmission1. Additional studies show that galanin and its receptors are involved in the transmission and modulation of nociception of the central nervous system, at spinal cord levels and in the brain2.
- Molecular Weight
- 3157 Da
- UniProt
- P22466
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