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Prolactin (PRL) (AA 29-227) Peptide

PRL Reactivity: Human Host: Escherichia coli (E. coli) SDS
Catalog No. ABIN934935

Quick Overview for Prolactin (PRL) (AA 29-227) Peptide (ABIN934935)

Target

Prolactin (PRL)

Origin

Human

Source

  • 5
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)
  • Peptide Type

    Recombinant

    Protein Region

    AA 29-227

    Sequence

    MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC

    Characteristics

    Purified recombinant Human Prolactin protein
    Expression System: E.coli
    Molecular weight on SDS-PAGE will appear higher.

    Purity

    > 95 % pure
  • Application Notes

    Prolactin protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Supplied as a liquid in PBS, pH 7.4.

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    RT/-20 °C

    Storage Comment

    Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
  • Target

    Prolactin (PRL)

    Background

    Prolactin is a hormone synthesised and secreted by lactotrope cells in the adenohypophysis (anterior pituitary gland). Prolactin has many effects, the most significant of which is to stimulate the mammary glands to produce milk (lactation). Increased serum prolactin during pregnancy causes enlargement of the mammary glands of the breasts and increases the production of milk. Recently, prolactin has demonstrated broader roles in breast cancer development, regulation of reproductive function, and immunoregulation. Prolactin was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
    Alternative Names: Mammotropin protein, Prolactin precursor., Lactogenic hormone protein, PRL protein, Prolactin protein, OTTHUMP00000017727 protein, Luteotropic hormone protein

    Molecular Weight

    23 kDa (200 AA)
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