Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) Peptide
BMP4
Reactivity: Human
Host: Escherichia coli (E. coli)
SDS
1 image
Catalog No. ABIN935014
Quick Overview for Bone Morphogenetic Protein 4 (BMP4) (AA 293-408) Peptide (ABIN935014)
Target
BMP4
(Bone Morphogenetic Protein 4 (BMP4))
Origin
Human
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
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Peptide Type
- Recombinant
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Protein Region
- AA 293-408
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Sequence
- MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR
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Characteristics
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Purified recombinant Human BMP4 protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. -
Purity
- > 95 % pure
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Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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Application Notes
- BMP4 protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied as a liquid in 10 mM sodium citrate buffer, pH 3.5, containing 10 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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Background
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Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: Bone morphogenetic protein 4 BMP 4 protein, BMP 4 protein, DVR4 protein, BMP 4, BMP-4 protein, BMP-4, BMP-2B protein, BMP4, ZYME., BMP2B1 protein, BMP2B protein -
Molecular Weight
- 13.2 kDa (117 AA)
Target
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