Ornithine Aminotransferase (OAT) (AA 33-439) Peptide
OAT
Reactivity: Human
Host: Escherichia coli (E. coli)
SDS
1 image
Catalog No. ABIN935082
Quick Overview for Ornithine Aminotransferase (OAT) (AA 33-439) Peptide (ABIN935082)
Target
OAT
(Ornithine Aminotransferase (OAT))
Origin
Human
Source
Escherichia coli (E. coli)
Application
SDS-PAGE (SDS)
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Peptide Type
- Recombinant
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Protein Region
- AA 33-439
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Sequence
- MTVQGPPTSD DIFEREYKYG AHNYHPLPVA LERGKGIYLW DVEGRKYFDF LSSYSAVNQG HCHPKIVNAL KSQVDKLTLT SRAFYNNVLG EYEEYITKLF NYHKVLPMNT GVEAGETACK LARKWGYTVK GIQKYKAKIV FAAGNFWGRT LSAISSSTDP TSYDGFGPFM PGFDIIPYND LPALERALQD PNVAAFMVEP IQGEAGVVVP DPGYLMGVRE LCTRHQVLFI ADEIQTGLAR TGRWLAVDYE NVRPDIVLLG KALSGGLYPV SAVLCDDDIM LTIKPGEHGS TYGGNPLGCR VAIAALEVLE EENLAENADK LGIILRNELM KLPSDVVTAV RGKGLLNAIV IKETKDWDAW KVCLRLRDNG LLAKPTHGDI IRFAPPLVIK EDELRESIEI INKTILSF
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Characteristics
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Purified recombinant Human OAT protein
Expression System: E.coli -
Purity
- > 90 % pure
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Application Notes
- OAT protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 10 % glycerol.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- RT/-20 °C
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Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- OAT (Ornithine Aminotransferase (OAT))
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Background
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OAT, also known as mitochondrial enzyme ornithine aminotransferase, is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Recombinant OAT protein was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: OATASE protein, HOGA protein, Ornithine aminotransferase protein, Ornithine--oxo-acid aminotransferase., mitochondrial precursor protein, DKFZp781A11155 protein, ornithine aminotransferase precursor protein, ornithine aminotransferase (gyrate atrophy) protein, ornithine aminotransferase precursor EC 2.6.1.13 protein, Ornithine oxo-acid aminotransferase protein -
Molecular Weight
- 45.2 kDa (408 AA)
Target
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