Vasodilator-Stimulated phosphoprotein (VASP) Peptide
VASP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN935974
Quick Overview for Vasodilator-Stimulated phosphoprotein (VASP) Peptide (ABIN935974)
Target
VASP
(Vasodilator-Stimulated phosphoprotein (VASP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- WSVPNGPSPE EVEQQKRQQP GPSEHIERRV SNAGGPPAPP AGGPPPPPGP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of VASP antibody,
Alternative Names: VASP control peptide, VASP antibody Blocking Peptide, Anti-VASP Blocking Peptide, vasodilator-stimulated phosphoprotein Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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Background
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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Molecular Weight
- 42 kDa
Target
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