B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) Peptide
BCL11A
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN935999
Quick Overview for B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A) Peptide (ABIN935999)
Target
BCL11A
(B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YACAQSSKLT RHMKTHGQVG KDVYKCEICK MPFSVYSTLE KHMKKWHSDR
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of BCL11 A antibody,
Alternative Names: BCL11A control peptide, BCL11A antibody Blocking Peptide, Anti-BCL11A Blocking Peptide, B-cell CLL/lymphoma 11A, zinc finger protein Blocking Peptide, BCL11A-L Blocking Peptide, BCL11A-S Blocking Peptide, BCL11A-XL Blocking Peptide, CTIP1 Blocking Peptide, EVI9 Blocking Peptide, FLJ10173 Blocking Peptide, FLJ34997 Blocking Peptide, HBFQTL5 Blocking Peptide, KIAA1809 Blocking Peptide, ZNF856 Blocking Peptide, BCL11A, BCLA-11, BCLA 11, BCLA-11 Blocking Peptide, BCLA 11 Blocking Peptide -
Purification
- Cellsupernatant, Protein G purified, 50 mM TRIS pH 7,4 0,04% Thimerosal
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))
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Background
- BCL11A is a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression.
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Molecular Weight
- 91 kDa
Target
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