Minichromosome Maintenance Complex Component 3 (MCM3) Peptide
MCM3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936013
Quick Overview for Minichromosome Maintenance Complex Component 3 (MCM3) Peptide (ABIN936013)
Target
MCM3
(Minichromosome Maintenance Complex Component 3 (MCM3))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTRQPDAK
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of MCM3 antibody,
Alternative Names: MCM3 control peptide, MCM3 antibody Blocking Peptide, Anti-MCM3 Blocking Peptide, Minichromosome Maintenance Complex Component 3 Blocking Peptide, HCC5 Blocking Peptide, MGC1157 Blocking Peptide, P1-MCM3 Blocking Peptide, P1.h Blocking Peptide, RLFB Blocking Peptide, MCM3, MCM-3, MCM 3, MCM-3 Blocking Peptide, MCM 3 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
-
Background
- MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
-
Molecular Weight
- 91 kDa
Target
-
You are here:
