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Retinoic Acid Receptor, alpha (RARA) Peptide

RARA Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936051
  • Target See all Retinoic Acid Receptor alpha (RARA) products
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    YESVEVGGPT PNPFLVVDFY NQNRACLLPE KGLPAPGPYS TPLRTPLWNG
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of RARA antibody,
    Alternative Names: RARA control peptide, RARA antibody Blocking Peptide, Anti-RARA Blocking Peptide, Retinoic Acid Receptor Alpha Blocking Peptide, NR1B1 Blocking Peptide, RAR Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))
    Background
    Retinoid signaling is transduced by 2 families of nuclear receptors, retinoic acid receptor (RAR) and retinoid X receptor, which form RXR/RAR heterodimers. In the absence of ligand, DNA-bound RXR/RARA represses transcription by recruiting the corepressors NCOR1, SMRT, and histone deacetylase. When ligand binds to the complex, it induces a conformational change allowing the recruitment of coactivators, histone acetyltransferases, and the basic transcription machinery.
    Molecular Weight
    51 kDa
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