Adrenergic, alpha-1B-, Receptor (ADRA1B) Peptide
ADRA1B
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Quick Overview for Adrenergic, alpha-1B-, Receptor (ADRA1B) Peptide (ABIN936205)
Target
ADRA1B
(Adrenergic, alpha-1B-, Receptor (ADRA1B))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- YRPWTRGGSL ERSQSRKDSL DDSGSCLSGS QRTLPSASPS PGYLGRGAPP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of ADRA1 B antibody,
Alternative Names: ADRA1B control peptide, ADRA1B antibody Blocking Peptide, Anti-ADRA1B Blocking Peptide, adrenergic, alpha-1B-, receptor Blocking Peptide, ADRA1 Blocking Peptide, ALPHA1BAR Blocking Peptide, ADRA1B, ADRAB-1, ADRAB 1, ADRAB-1 Blocking Peptide, ADRAB 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
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Background
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
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Molecular Weight
- 57 kDa
Target
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