Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936790
Quick Overview for Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN936790)
Target
PYHIN1
(Pyrin and HIN Domain Family, Member 1 (PYHIN1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ANNYKKIVLL KGLEVINDYH FRIVKSLLSN DLKLNPKMKE EYDKIQIADL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PYHIN1 antibody,
Alternative Names: PYHIN1 control peptide, PYHIN1 antibody Blocking Peptide, Anti-PYHIN1 Blocking Peptide, pyrin and HIN domain family, member 1 Blocking Peptide, IFIX Blocking Peptide, MGC23885 Blocking Peptide, RP.1 Blocking Peptide, PYHIN1, PYHIN-1, PYHIN 1, PYHIN-1 Blocking Peptide, PYHIN 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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Background
- PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
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Molecular Weight
- 55 kDa
Target
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