Sorbitol Dehydrogenase (SORD) Peptide
SORD
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936895
Quick Overview for Sorbitol Dehydrogenase (SORD) Peptide (ABIN936895)
Target
SORD
(Sorbitol Dehydrogenase (SORD))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SORD antibody,
Alternative Names: SORD control peptide, SORD antibody Blocking Peptide, Anti-SORD Blocking Peptide, sorbitol dehydrogenase Blocking Peptide, SORD1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SORD (Sorbitol Dehydrogenase (SORD))
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Background
- Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
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Molecular Weight
- 38 kDa
Target
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