Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptide
FADD
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936923
Quick Overview for Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptide (ABIN936923)
Target
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ASVAGLVKAL RTCRLNLVAD LVEEAQESVS KSENMSPVLR DSTVSSSETP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Fadd antibody,
Alternative Names: FADD control peptide, FADD antibody Blocking Peptide, Anti-FADD Blocking Peptide, Fas Blocking Peptide, Tnfrsf6-Associated Via Death Domain Blocking Peptide, Mort1/FADD Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Background
- Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
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Molecular Weight
- 23 kDa
Target
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