Ribonucleotide Reductase M1 (RRM1) Peptide
RRM1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all RRM1 products
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- ATGSYIAGTN GNSNGLVPML RVYNNTARYV DQGGNKRPGA FAIYLEPWHL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RRM1 antibody,
Alternative Names: RRM1 control peptide, RRM1 antibody Blocking Peptide, Anti-RRM1 Blocking Peptide, Ribonucleotide Reductase M1 Polypeptide Blocking Peptide, R1 Blocking Peptide, RIR1 Blocking Peptide, RR1 Blocking Peptide, RRM1, RRM-1, RRM 1, RRM-1 Blocking Peptide, RRM 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Background
- RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.
- Molecular Weight
- 90 kDa
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