Ribonucleotide Reductase M1 (RRM1) Peptide
RRM1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936944
Quick Overview for Ribonucleotide Reductase M1 (RRM1) Peptide (ABIN936944)
Target
RRM1
(Ribonucleotide Reductase M1 (RRM1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ATGSYIAGTN GNSNGLVPML RVYNNTARYV DQGGNKRPGA FAIYLEPWHL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RRM1 antibody,
Alternative Names: RRM1 control peptide, RRM1 antibody Blocking Peptide, Anti-RRM1 Blocking Peptide, Ribonucleotide Reductase M1 Polypeptide Blocking Peptide, R1 Blocking Peptide, RIR1 Blocking Peptide, RR1 Blocking Peptide, RRM1, RRM-1, RRM 1, RRM-1 Blocking Peptide, RRM 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Background
- RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.
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Molecular Weight
- 90 kDa
Target
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