Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) Peptide
EGLN2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936989
Quick Overview for Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) Peptide (ABIN936989)
Target
PHD1 (EGLN2)
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- AVLDGSELSY FGQEGMTEVQ CGKVAFQFQC SSDSTNGTGV QGGQIPELIF
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of EGLN2 antibody,
Alternative Names: EGLN2 control peptide, EGLN2 antibody Blocking Peptide, Anti-EGLN2 Blocking Peptide, egl nine homolog 2, C. elegans Blocking Peptide, DKFZp434E026 Blocking Peptide, EIT6 Blocking Peptide, HIFPH1 Blocking Peptide, HPH-3 Blocking Peptide, PHD1 Blocking Peptide, EGLN2, EGLN-2, EGLN 2, EGLN-2 Blocking Peptide, EGLN 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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Background
- The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms. The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation.
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Molecular Weight
- 44 kDa
Target
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