8-Oxoguanine DNA Glycosylase (OGG1) Peptide
OGG1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN936997
Quick Overview for 8-Oxoguanine DNA Glycosylase (OGG1) Peptide (ABIN936997)
Target
OGG1
(8-Oxoguanine DNA Glycosylase (OGG1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of OGG1 antibody,
Alternative Names: OGG1 control peptide, OGG1 antibody Blocking Peptide, Anti-OGG1 Blocking Peptide, 8-oxoguanine DNA glycosylase Blocking Peptide, HMMH Blocking Peptide, HOGG1 Blocking Peptide, MUTM Blocking Peptide, OGH1 Blocking Peptide, OGG1, OGG-1, OGG 1, OGG-1 Blocking Peptide, OGG 1 Blocking Peptide -
Purification
- Protein A affinity column
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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Background
- This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
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Molecular Weight
- 35 kDa
Target
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