BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) Peptide
BNIP3L
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937057
Quick Overview for BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) Peptide (ABIN937057)
Target
BNIP3L/NIX (BNIP3L)
(BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Bnip3 l antibody,
Alternative Names: Bnip3l control peptide, Bnip3l antibody Blocking Peptide, Anti-Bnip3l Blocking Peptide, BCL2/adenovirus E1B interacting protein 3-like Blocking Peptide, C86132 Blocking Peptide, D14Ertd719e Blocking Peptide, Nip3L Blocking Peptide, Nix Blocking Peptide, Bnip3l, Bnipl-3, Bnipl 3, Bnipl-3 Blocking Peptide, Bnipl 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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Background
- Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
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Molecular Weight
- 24 kDa
Target
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