Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) Peptide
SIGLEC10
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all SIGLEC10 products
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- CHVDFSRKGV SAQRTVRLRV AYAPRDLVIS ISRDNTPALE PQPQGNVPYL
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SIGLEC10 antibody,
Alternative Names: SIGLEC10 control peptide, SIGLEC10 antibody Blocking Peptide, Anti-SIGLEC10 Blocking Peptide, Sialic Acid Binding Ig-Like Lectin 10 Blocking Peptide, MGC126774 Blocking Peptide, PRO940 Blocking Peptide, SIGLEC-10 Blocking Peptide, SLG2 Blocking Peptide, SIGLEC10, SIGLEC-10, SIGLEC 10, SIGLEC-10 Blocking Peptide, SIGLEC 10 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
- Background
- SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
- Molecular Weight
- 76 kDa
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