CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) Peptide
CTCFL
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937178
Quick Overview for CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) Peptide (ABIN937178)
Target
CTCFL
(CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CREKDHRSPS ELEAERTSGA FQDSVLEEEV ELVLAPSEES EKYILTLQTV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CTCFL antibody,
Alternative Names: CTCFL control peptide, CTCFL antibody Blocking Peptide, Anti-CTCFL Blocking Peptide, CCCTC-binding factor, zinc finger protein-like Blocking Peptide, BORIS Blocking Peptide, CTCF-T Blocking Peptide, MGC163358 Blocking Peptide, dJ579F20.2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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Background
- CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.
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Molecular Weight
- 76 kDa
Target
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