Exosome Complex Exonuclease RRP44 (DIS3) Peptide
DIS3
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937396
Quick Overview for Exosome Complex Exonuclease RRP44 (DIS3) Peptide (ABIN937396)
Target
DIS3
(Exosome Complex Exonuclease RRP44 (DIS3))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DIVAVELLPK SQWVAPSSVV LHDEGQNEED VEKEEETERM LKTAVSEKML
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DIS3 antibody,
Alternative Names: DIS3 control peptide, DIS3 antibody Blocking Peptide, Anti-DIS3 Blocking Peptide, Dis3 Mitotic Control Homolog Blocking Peptide, DKFZp667L1817 Blocking Peptide, FLJ10484 Blocking Peptide, KIAA1008 Blocking Peptide, MGC33035 Blocking Peptide, RP.3 Blocking Peptide, RRP44 Blocking Peptide, bA555G22.1 Blocking Peptide, dis3p Blocking Peptide, DIS3, DIS-3, DIS 3, DIS-3 Blocking Peptide, DIS 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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Background
- DIS3, belonging to the ribonuclease II (RNB) family, has a 3'-5' exonuclease activity. It is a catalytic component of the exosome 3'->5' exoribonuclease complex required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay. The protein is implicated in mitotic control and essential for cell division and spore germination. It may be involved in regulating protein dephosphorylation during mitosis.
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Molecular Weight
- 109 kDa
Target
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