Transmembrane Protein 173 (TMEM173) Peptide
TMEM173
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937495
Quick Overview for Transmembrane Protein 173 (TMEM173) Peptide (ABIN937495)
Target
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TMEM173 antibody,
Alternative Names: TMEM173 control peptide, TMEM173 antibody Blocking Peptide, Anti-TMEM173 Blocking Peptide, Transmembrane Protein 173 Blocking Peptide, FLJ38577 Blocking Peptide, TMEM173, TMEM-173, TMEM 173, TMEM-173 Blocking Peptide, TMEM 173 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Background
- TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
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Molecular Weight
- 42 kDa
Target
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