3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) Peptide
BPNT1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937539
Quick Overview for 3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) Peptide (ABIN937539)
Target
BPNT1
(3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of BPNT1 antibody,
Alternative Names: BPNT1 control peptide, BPNT1 antibody Blocking Peptide, Anti-BPNT1 Blocking Peptide, 3' 2' 5'-bisphosphate nucleotidase 1 Blocking Peptide, 2', 5'-Bisphosphate Nucleotidase 1 Blocking Peptide, PIP Blocking Peptide, BPNT1, BPNT-1, BPNT 1, BPNT-1 Blocking Peptide, BPNT 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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Background
- BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
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Molecular Weight
- 29 kDa
Target
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