Runt-Related Transcription Factor 2 (RUNX2) Peptide
RUNX2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937574
Quick Overview for Runt-Related Transcription Factor 2 (RUNX2) Peptide (ABIN937574)
Target
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RUNX2 antibody,
Alternative Names: RUNX2 control peptide, RUNX2 antibody Blocking Peptide, Anti-RUNX2 Blocking Peptide, Runt-Related Transcription Factor 2 Blocking Peptide, RUNX2, RUNX-2, RUNX 2, RUNX-2 Blocking Peptide, RUNX 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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Background
- RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
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Molecular Weight
- 57 kDa
Target
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