Amyloid beta (A4) Precursor Protein (APP) Peptide
APP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937650
Quick Overview for Amyloid beta (A4) Precursor Protein (APP) Peptide (ABIN937650)
Target
APP
(Amyloid beta (A4) Precursor Protein (APP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EAKHRERMSQ VMREWEEAER QAKNLPKADK KAVIQHFQEK VESLEQEAAN
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of APP antibody,
Alternative Names: APP control peptide, APP antibody Blocking Peptide, Anti-APP Blocking Peptide, Amyloid Precursor Protein Blocking Peptide, AAA Blocking Peptide, ABETA Blocking Peptide, ABPP Blocking Peptide, AD1 Blocking Peptide, APPI Blocking Peptide, CTFgamma Blocking Peptide, CVAP Blocking Peptide, PN2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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Background
- APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
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Molecular Weight
- 77 kDa
Target
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