Proline Rich Gla (G-Carboxyglutamic Acid) 1 (PRRG1) Peptide
Quick Overview for Proline Rich Gla (G-Carboxyglutamic Acid) 1 (PRRG1) Peptide (ABIN937682)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- ECKEEFCTFE EAREAFENNE KTKEFWSTYT KAQQGESNRG SDWFQFYLTF
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PRRG1 antibody,
Alternative Names: PRRG1 control peptide, PRRG1 antibody Blocking Peptide, Anti-PRRG1 Blocking Peptide, Proline Rich Gla Blocking Peptide, G-Carboxyglutamic Acid 1 Blocking Peptide, PRGP1 Blocking Peptide, PRRG1, PRRG-1, PRRG 1, PRRG-1 Blocking Peptide, PRRG 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PRRG1 (Proline Rich Gla (G-Carboxyglutamic Acid) 1 (PRRG1))
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Background
- PRRG1 encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene.
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Molecular Weight
- 25 kDa
Target
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