Periplakin (PPL) Peptide
PPL
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937909
Quick Overview for Periplakin (PPL) Peptide (ABIN937909)
Target
PPL
(Periplakin (PPL))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PPL antibody,
Alternative Names: Periplakin control peptide, Periplakin antibody Blocking Peptide, Anti-Periplakin Blocking Peptide, KIAA0568 Blocking Peptide, MGC134872 Blocking Peptide, PPL Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PPL (Periplakin (PPL))
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Background
- PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
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Molecular Weight
- 205 kDa
Target
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