Minichromosome Maintenance Deficient 8 (MCM8) Peptide
MCM8
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937955
Quick Overview for Minichromosome Maintenance Deficient 8 (MCM8) Peptide (ABIN937955)
Target
MCM8
(Minichromosome Maintenance Deficient 8 (MCM8))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- ELRDAPEKTL ACMGLAIHQV LTKDLERHAA ELQAQEGLSN DGETMVNVPH
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MCM8 antibody,
Alternative Names: MCM8 control peptide, MCM8 antibody Blocking Peptide, Anti-MCM8 Blocking Peptide, Minichromosome Maintenance Complex Component 8 Blocking Peptide, MCM8, MCM-8, MCM 8, MCM-8 Blocking Peptide, MCM 8 Blocking Peptide -
Purification
- Immunoaffinity chromatography
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
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Background
- MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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Molecular Weight
- 92 kDa
Target
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